More than half of us will spend the day complaining, particularly in the morning.
The average respondent in the survey spent 34 minutes moaning on a Monday morning, compared to just 22 minutes during the rest of the week.
One in three people said they hated Monday more than any other day of the week.
Some of the most common reasons include dreading the working week ahead, over-indulging over the weekend or having a mountain of emails to catch up with.
Other explanations in the top ten of Monday moans include feeling tired and taking a while to get back into 'work mode'.
A spokesman for Flomax Relief, which conducted the research of 2,000 adults said:
'Feeling a bit down and under the weather is a common Monday morning problem.
: One in three said they hated Mondays, many because they dread the working week
'In fact, the average respondent moans for around 34 minutes on a Monday morning, compared to just 22 minutes during the rest of the week.
'And while people continue to grumble about aches and pains, heavy workloads and tiredness the rest of the week, Mondays tend to be when people suffer most.'
But things get little better as the week progress, as Brits continue to moan about the amount of work they have to do, traffic, inefficiency and ill health. In fact, common grumbles on the biggest moan day of the week include feeling stressed with everything that needs to be done, and managing an enormous work load.
Top 10 Monday moans....
1. You dread your working week
2. You always feel more tired on a Monday than any other day
3. You're already missing the weekend
4. It takes you a while to get back into work
5. You had too many late nights over the weekend
6. You over-indulged on food and drink at the weekend
7. You had a particularly active couple of days
8. You always have a mountain of emails to catch up on
9. You spent much of the weekend travelling around
10. You always feel a bit poorly on a Monday
Other work related complaints include contending with a slow booting computer, getting stuck in traffic on the way to the office and the feeling that you are trying to keep everyone happy.
Other factors people are most likely to moan about include being kept on hold for longer than a minute, the weather forecasters getting it wrong and poor customer service.
Personal grievances such as a bad hair diary, aches and pains, feeling 'fat' and having nothing to wear also put people in a bad mood.
The Flomax Relief
'While there appears to be a range of reasons that can affect our mood, especially on a Monday, it would seem that health-related problems are one of the biggest triggers.
'This suggests that, as a nation, taking better care of our health may help improve our general well-being and happiness.'